The Maturing Brain Methylome

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Maturing Brain: His and Hers

A12-year-old brain possesses almost all of the neurons that it will ever have, but still has some maturing to do. Throughout the rest of adolescence and into adulthood, this organ will refine its white matter tracts. These bundles of axon fibers function as the wires in the circuits that connect the neurons in the brain’s many regions. Their carrying capacity and speed determine the degree of c...

متن کامل

Cannabis and the maturing brain: Role in psychosis development.

A common viewpoint has proliferated that cannabis use is mostly harmless. Some argue that by not supporting its use, we are missing a great therapeutic opportunity. The general public view on cannabis may partially be a result of poor knowledge translation. In fact, the "war on drugs" approach has not allowed for basic education on the varied effects of cannabis on the brain, especially at high...

متن کامل

Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing

Reduced representation bisulfite sequencing (RRBS) has been used to profile DNA methylation patterns in mammalian genomes such as human, mouse and rat. The methylome of the zebrafish, an important animal model, has not yet been characterized at base-pair resolution using RRBS. Therefore, we evaluated the technique of RRBS in this model organism by generating four single-nucleotide resolution DN...

متن کامل

Neuroanatomical prerequisites for language functions in the maturing brain.

The 2 major language-relevant cortical regions in the human brain, Broca's area and Wernicke's area, are connected via the fibers of the arcuate fasciculus/superior longitudinal fasciculus (AF/SLF). Here, we compared this pathway in adults and children and its relation to language processing during development. Comparison of fiber properties demonstrated lower anisotropy in children's AF/SLF, a...

متن کامل

The human placental methylome.

This review provides an overview of the unique features of DNA methylation in the human placenta. We discuss the importance of understanding placental development, structure, and function in the interpretation of DNA methylation data. Examples are given of how DNA methylation is important in regulating placental-specific gene expression, including monoallelic expression and X-chromosome inactiv...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Science

سال: 2013

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.1242671